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Select first clinical development candidate in oncology alliance
December 9, 2013
By: Kristin Brooks
Managing Editor, Contract Pharma
Oxford BioTherapeutics (OBT) and Berlin-Chemie (Menarini Group) have selected a novel enhanced antibody targeting acute myeloid leukemia (AML) as the first clinical candidate under the companies’ oncology collaboration. The companies have initiated studies to support an application for a Phase I trial in AML patients in 2H14. The therapeutic candidate incorporates BioWa ADCC-enhancing technology and has completed in vitro/ex vivo proof-of-concept, demonstrating efficacy, and exploratory ...
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